More Than Engaging with Government – Let’s Work Together

On November 2, 2017, I had the pleasure and opportunity to represent LifeSciences BC board, together with Nancy Harrison, Chair, Board of Directors, Dr. Lesley Esford, President & CEO, along with other board members, Dr. Pieter Cullis and Scott Phillips. Our visit included breakfast with the NDP caucus and lunch with the Liberal caucus, where Dr. Esford presented an overview of the life sciences sector in B.C.

What we shared with government were several impressive and enlightening facts:

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Why Did We Go Fishing with Roche Venture Fund?

We were delighted to host Karl Handelsman, Partner at Roche Venture Fund in Vancouver last week.

Over 100 participants came to his talk at BC Cancer Agency where he talked about “Winning Strategies for Biotech Startups”. Afterwards, we held a private dinner where he met several companies he had expressed interest in connecting with. The following day we went on a fishing trip with where Karl had an opportunity to connect with the biotech entrepreneurs one on one for several hours.

Why did we invite Karl?

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Companion Diagnostics: A Guide to Cure?

There is an obsession by biotechs, pharma, investors and payers to pre-select responders to a therapy before they are treated.

How did we end up here and how is this going to impact medicine in the long term? In certain diseases where the biology landscape is understood better, like oncology, there has been tremendous impact. However, in most other target areas we still cannot isolate the responders and use “all comers” to try treatments and hope the safety and efficacy of a drug can be shown to be statistically significant. What happens to target areas where specific responders cannot be identified?

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Forgoing Retirement: Why I Became an Advisor at Novateur Ventures

I have had a successful career in pharmaceutical development and operations and I was about to retire but decided not to. So why am I an Advisor at Novateur Ventures?

I just saw a quote from astrophysicist Neil Degrasse Tyson and this answers part of the reason for my motivation.

“When I think of science and scientists, I think of kids who never lost their curiosity and wonder, and then woke up one day as adults with the same sense of search for what is and what is not true in the world.”

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Entrepreneurial Pharma: Confronting the Adage, “Experience Is Something You Get Just After You Need It.”

During my 23 years working in the entrepreneurial pharma environment I have witnessed many lessons learned and I continue to see many companies focusing primarily on reaching key funding milestones while neglecting good drug development practices. This is a mindset that can cost them dearly and deliver experience after it’s needed!

It is crucial for entrepreneurs to focus on creating a strong value proposition for the company, attracting the top investors and scientific advisors and moving quickly to key milestones and the additional funding they provide. It’s the nature of the environment.

However, at the same time, pharma development requires early and consistent compliance with regulatory guidelines and quality assurance standards and exemplary collaboration skills to enable critical preclinical and clinical trials.

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How Trump Presidency and BREXIT Are Creating the Perfect Storm for Reversing Canada’s Brain Drain

Historically Canada has faced a significant challenge in attracting top talent compared to the United States and retaining top talent already in Canada.

Until recently, top entrepreneurs would often choose to start their next big idea in the US, for several reasons, including:
Better access to capital
Better access to talent
Lower income taxes

The results of the 2016 presidential election and BREXIT have changed this. For the first time, some of the top US, UK and international executives and entrepreneurs are considering relocation to Canada.

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Conquering the South Pole and Lessons for Biotechs

How the Norwegians conquered the South Pole while the well funded and well resourced British all died on the way back & how that applies to biotech

December 14th, 2016 marked the 105th anniversary of the first expedition to the South Pole by the Norwegian Roald Amundsen, trained by the Inuit in Canada. Famously, the second place finishers, a British team led by Robert Scott, showed up at the South Pole 34 days later. Despite starting the race much earlier with significantly more men and resources, the Brits not only faced defeat, but also died on the return journey.

This race in many ways reflects two different business models. What we can learn from it is especially applicable to biotechs and pharma.

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How Would the Biotech Landscape Change After the Election?

As members of the life science community and organizations lobbying for our sector, we ought to do a better job educating the public on a tall task we have chosen for our careers. No other sector is as risky as the life science sector and many of us as life science entrepreneurs end up risking our savings and spend our careers trying to bring new medicines to patients. Many of these ventures do not ever make it. The true value of the drug, the expense and risk that takes to bring a medicine to patients, needs to be better communicated.

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